Abstract
The third component of complement (C'3) has been defined in terms of its role in a hemolytic system. It is also known as the component which is inactivated by cobra venom or by yeast. In an attempt to discover which fraction of yeast inactivated C'3, Pillemer and Ecker1 succeeded in isolating an insoluble carbohydrate from yeast which destroys or removes the activity of C'3 in amounts vastly smaller than the whole yeast or the zymin preparation of Whitehead, Gordon and Wormall.2 For the sake of simplicity this insoluble carbohydrate will henceforth be called zymosan† It was suggested that the inactivation of complement by yeast was due to the adsorption of C'3 on this carbohydrate. In a subsequent paper Ecker, Jones and Kuehn3 noted that in the presence of 10% NaCl zymin did not inactivate C'3. Likewise, it has since been found that 10% NaCl suppresses the adsorption of C'3 by zymosan.In the light of these facts it was therefor proposed to study the adsorbate with regard to the uptake of nitrogen. A stock...
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call