Abstract
Chromatographic retention parameters k' and kW were determined by RP-HPLC for a set of standard non-congeneric compounds and the correlation with log Po/W established. Then, log Po/W was calculated for a series of antimicrobial hydrazides, as a test set. A comparison of the chromatographic parameters log k' and log KW with the hydrophobicity index ϕ0 were also made. It seems that for the study compounds, log KW describes the partitioning better than the parameter ϕ0. †Work presented at the International Symposium on Lipophilicity and Toxicology, Lausanne, Switzerland, 21–24 March, 1995.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Liquid Chromatography & Related Technologies
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
