Abstract
Objective: The objective of the current study was to estimate the energy spectrum and energy deposition of the photons emitted from 125I seed model 6711 with and without the presence of titanium capsule using Monte-Carlo N-Particle code (MCNP) in order to investigate whether the titanium capsule attenuates photons and how much would be the attenuation. Materials and Methods: Two models were built and simulated using MCNPX code, in the first model, the simulation was performed assuming the geometry of 125I seed provided by the manufacturers. Whereas in the second model, the simulation was performed assuming that 125I seed without titanium encapsulation. For both models, the energy and energy deposition of the photons were estimated. Results: MCNPX computations showed that the energy spectrum released from 125I seed with the presence of the capsule was lower than that released without the presence of the capsule for all energies in the spectrum by approximately 19 %. Further, the energy deposition computed with the presence of titanium capsule was lower than that computed without the presence of titanium capsule by nearly 31%. Conclusion: The titanium capsule has an impact on the energy spectrum as well as energy deposition of the photons emitted by 125I seed. According to the MCNPX results, titanium capsule attenuates the energy and energy deposition of the radiation emerged from the seed by nearly 19% and 31% respectively. Keywords: Brachytherapy, Energy Deposition, Energy Spectrum, 125I Seed, Model 6711, MCNP
Highlights
Interstitial brachytherapy using permanent radioactive implants is a common choice for most patients with prostate cancer[1,2,3]
The current study was designed to estimate the energy spectrum and energy deposition of the photons emitted from 125I source with and without the presence of titanium capsule using Monte-Carlo N- Particle code (MCNP) in order to investigate whether the titanium capsule attenuates photons
The results of the current study indicated that the energy spectrum of the photons emitted by the 125I source is attenuated by the titanium capsule as well as through the space between the source and the encapsulation
Summary
Interstitial brachytherapy using permanent radioactive implants is a common choice for most patients with prostate cancer[1,2,3]. Three commercial models of 125I seed have been manufactured, which are 6701, 6702, and 6711 These models are similar in encapsulation and size but different in the design of active source[5]. Very low-energy x-ray of 3.8 keV is possible (15%) but in practice very low energy photons are attenuated within the source capsule”[9].The production and decay processes of 125I are shown in the equations below[9]. Iodine-125 emits gamma and x-photons with spectrum of energies ranges from 3.3 to 35.5 Kev[10]. The current study was designed to estimate the energy spectrum and energy deposition of the photons emitted from 125I source with and without the presence of titanium capsule using Monte-Carlo N- Particle code (MCNP) in order to investigate whether the titanium capsule attenuates photons
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