Abstract
We have provided an evidence-based framework for estimating the public-health burden of P. falciparum malaria1 by using a uniform series of structured, transparent and reproducible data and methods to define the cartography of this parasite's clinical impact at a global scale. This contribution to global disease modelling is questioned by Nahlen .2 for United Nations agencies responsible for measuring development targets (see also ref. 3), and our estimation of the malaria burden outside Africa is challenged by Bell .4.
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