Estimates of Body Composition in Drug Naïve Asymptomatic HIV‐infected Rural Kenyan Women

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ObjectiveBioelectrical impedance analysis (BIA), as a method to estimate fat free mass (FFM) and % body fat (%BF), is compared to the anthropometric (Anthro) method using skinfold (SF) and body circumference (BC) measures in HIV‐infected women in rural Kenya.MethodsIn 138 women, (WHO Stage 1 or 2; CD4 > 250 cells/uL), height, weight, SF, BC and BIA were obtained with standardized procedures. Fat area of the arm (MAFA), muscle area of the arm (MAMA), thigh (MTMA), calf (MCMA) and sum of SF were calculated from standard equations using BC and SF. Estimates of FFM, %BF and total body water (TBW) from BIA measures of resistance were calculated with standard equations.ResultsThe mean (SD) for age, BMI and CD4 was 36.4(7.5) yrs, 22.3(3.6); 11% < 18.5, and 492(191) cells/uL, respectively. Anthro compared to BIA for estimates of lean and fat mass Anthro MAMA MTMA MCMA MAMA MAFA Sum SF BIA FFM FFM FFM TBW %BF %BF __ r 0.61 0.70 0.71 0.65 0.84 0.87 __ All correlations p<0.001 ConclusionsBIA, when compared to the method using anthropometry measures, has a strong relationship to fat and lean mass, at baseline, in drug naïve asymptomatic HIV‐infected rural Kenyan women enrolled in an 18 month randomized controlled field trial that measures the impact of added protein and energy on body composition. Supported in part by USAID Grant No. PCE‐G‐00‐98‐00036‐00 and 1R01HD57646‐01A1 (CFDA #93.865)