Abstract
Hepatitis A vaccination is justified in areas with an intermediate endemicity of the infection.To estimate the epidemiological impact of hepatitis A infection in Colombia.Epidemiological indicators of hepatitis A infection prevalence by age, morbidity by age, and lethality by age were estimated from a literature search. These measures were projected on a hypothetical cohort of children followed from birth until 15 years of age. The number of cases of infection, jaundice, hepatic failure, hospitalizations and deaths were estimated.From birth to adolescence, a cohort of 872 923 urban children in Colombia would generate between 312,331 and 598,591 infections, between 13,586 and 25,960 hospitalizations, between 213 and 407 hepatic failures and between 107 and 204 deaths.The impact of hepatitis A infection in Colombia, is important. Introducing hepatitis A vaccination would reduce a substantial number of severe hepatitis A cases.
Highlights
Hepatitis A vaccination is justified in areas with an intermediate endemicity of the infection
Material and Methods: Epidemiological indicators of hepatitis A infection prevalence by age, morbidity by age, and lethality by age were estimated from a literature search
Introducing hepatitis A vaccination would reduce a substantial number of severe hepatitis A cases. (Rev Med Chile 2010; 138: 994-999)
Summary
Estimación del impacto de la infección por Hepatitis A en zonas urbanas de Colombia 2008. Un análisis a partir de datos secundarios. Financiamiento: El presente estudio fue financiado por el Ministerio de la Protección Social de Colombia en convenio con la Universidad Nacional de Colombia. Recibido el 24 de agosto de 2009, aceptado el 9 de agosto de 2010. Grupo de Investigación en Economía de la Salud, Universidad de Cartagena. NELSON ALVIS1, BIBIANA PÉREZ2, JAVIER NARVAEZ2, MARTHA VELANDIA3, FERNANDO DE LA HOZ2. Theoretical estimation of the epidemiological impact of hepatitis A infection in Colombia
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