Abstract
BackgroundRespiratory syncytial virus infection is the leading cause of bronchiolitis in Colombia. There is growing evidence about the impact of Respiratory syncytial virus on society in terms of years of life lost due to this condition. The objective of the present study is to determine the Disability-Adjusted Life Years for respiratory syncytial virus in children under 2 years in Colombia.MethodsData from the national epidemiological surveillance system were used to estimate DALYs, calculated from the sum of years of life lost and years lived with disability due to RSV infection in Colombia. A bootstrapped method with 10,000 iterations was used to estimate each statistical parameter using the package DALY calculator in R.ResultsIn 2019, 260,873 years of life (CI95% 208,180–347,023) were lost due to RSV bronchiolitis in Colombian children under 2 years. The estimated rate was 20 DALYs / 1000 person-year (95% CI 16–27).ConclusionThis is the first report estimating the impact of RSV bronchiolitis morbidity and mortality in Colombia. The findings of the present study suggest that the actual burden and cost of bronchiolitis due to RSV is high. Prevention strategies, such as RSV vaccination, to reduce morbidity associated with RSV infection should be encouraged in our country.
Highlights
Respiratory syncytial virus infection is the leading cause of bronchiolitis in Colombia
The burden of disease is evaluated using the disability-adjusted life year (DALY), a time-based measure that link years of life lost due to premature mortality (YLLs) and years of life lost due to time lived in states of less than full health, or years of healthy life lost due to disability (YLDs)
The estimated rate was 20 DALYs / 1000 person-year. 51-% (1694 DALYs) were occurred in male children, and 63.19% of DALYs affected children between 1 to 2 years of age (Table 2). 99% of DALYs represented years of life lost due to early death
Summary
Respiratory syncytial virus infection is the leading cause of bronchiolitis in Colombia. The objective of the present study is to determine the Disability-Adjusted Life Years for respiratory syncytial virus in children under 2 years in Colombia. Respiratory syncytial virus (RSV) is the most frequent cause of bronchiolitis worldwide. This virus causes 33.1 million episodes of RSV lower respiratory tract illness (LRTI), 3.2 million hospital admissions, and 59,600 inhospital deaths in children younger than 5 years [1]. One DALY means the loss of the equivalent of 1 year of full health [5]. With this measure we can be estimated diseases that do not cause
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