Abstract
Establishment of reference intervals of thyroid function test in healthy individuals - IJCBR- Print ISSN No: - 2394-6369 Online ISSN No:- 2394-6377 Article DOI No:- 10.18231/2394-6377.2018.0053, International Journal of Clinical Biochemistry and Research-Int J Clin Biochem Res
Highlights
Interpretation of medical laboratory data is an example of decision making by comparision
The concept of reference intervals was introduced by the International Federation of Clinical Chemistry (IFCC) to avoid problems with normal values and values obtained from individuals under clinical investigation
Very few studies have been done for establishing reference range for TFT namely thyroid stimulating hormone(TSH), total thyroxine(T4), total triiodothyronine(T3); for healthy adult population in India
Summary
Interpretation of medical laboratory data is an example of decision making by comparision. In the 2010 clinical and laboratory standards institute(CLSI) guidelines, this point has been emphasised.[5] Currently very few studies have been done for establishing reference range for TFT (thyroid function test) namely thyroid stimulating hormone(TSH), total thyroxine(T4), total triiodothyronine(T3); for healthy adult population in India. The reference values of TFT used in clinical laboratories have been adopted from those reported for the western population These reference intervals in most of the cases cannot be taken into acount in our set up because serum TFT levels even in healthy normal population are affected by a number of factor such as age, sex, racial differences, dietary factors, socio-economic status and geographic conditions. Thyroid hormones maintain the basal metabolic rate and regulates the metabolism of endogenous and exogenous substances.[7,8] the current study was aimed at establishing the reference range of TFT in adult healthy population in Anand district, Gujarat, India
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