Abstract
Primary immunodeficiency disease (PID) are rare diseases caused by inherent defects of the immune system, the main clinical manifestations are increased susceptibility to infections, autoimmune diseases and malignancies.For such rare diseases, it's essential to establish national patient online database for collaborative studies.By using hypertext preprocessor (PHP)and MySQL, the database and registration system are successfully set up, and it could complete inquiries for the information saving, export, query, retrieval, backup etc.This database includes patient's information on the diagnosis, clinical manifestations, laboratory examinations, treatments.Through communication and information-sharing between multiple centers, it creates a basis for nationwide research on PID. Key words: Primary immunodeficiency disease; Registry; Database
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