Abstract
A new T-cell line. Loucy, was established from the peripheral blood of a patient with T-cell acute lymphoblastic leukemia (T-ALL). The surface marker analysis of the cell line is OKT3+, OKT4+, THB4+, J5±, OKT6−, TdT−, and HLA-DR−. indicating stage IV in T-cell lineage. Karyotype analysis revealed 45,X.5q−,t(16;20)(p12;q13). The translocation between chromosomes 16 and 20 has not been previously detected in ALL. This cell line may be of value in evaluating the role of t(16;20) in the etiology of T-ALL.
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