Abstract
Having emerged as an ideal solution against pathogenic microorganisms, antimicrobial medication seems to have lost the battle today. The ability of the living world to survive and adapt exceeds the synthetic products power of action, leading us today to a real crisis of microbial resistance to antibiotics. An unexpected solution may come also from the bosom of nature, by reconsidering the role and place of the essential oils as antimicrobial combat weapons. Defensive mechanisms created by nature, the essential oils demonstrate extraordinary antibacterial, antiviral and antifungal activity. They also help the synthetic antibiotics in their battle. Among the essential oils and the antibiotics, often intervene synergistic or additive interactions. The essential oils favor the antibiotics to penetrate through the cell wall and to extend their action spectrum. Undoubtedly, essential oils can be of crucial help in the current medical practice, through their complex antibacterial, antiviral and antifungal action.
Highlights
Since Paul Ehrlich introduced the term chemotherapy, meaning a treatment based on chemical substances
If before 1913, the medicine used mainly natural products under various forms containing hundreds or thousands of chemical substances, starting with Paul Ehrlich came a change in the therapy perspective, by introduction of the mono-compound drugs
Alarm signs come from the World Health Organization, which states in a report from 2012 the following, regarding the resistance to antibiotics: “Antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi
Summary
Since Paul Ehrlich introduced the term chemotherapy, meaning a treatment based on chemical substances. With some Gram-negatives, resistance may involve most or even all the available antimicrobial options, resulting in extremely drugresistant or totally drug-resistant phenotypes. This so-called ‘antibiotic resistance crisis’ has been compounded by the lagging in antibiotic discovery and development programs occurred in recent. Some CRE bacteria have become resistant to most available antibiotics Infections with these germs are very difficult to treat, and can be deadly—one report cites they can contribute to death in up to 50% of patients who become infected.” [4]. Alarm signs come from the World Health Organization, which states in a report from 2012 the following, regarding the resistance to antibiotics: “Antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. The return towards nature and to the infinite possibilities which nature offers us, may be one of these solutions
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