Abstract
Esomeprazole is the S-isomer of omeprazole. Results of pharmacokinetic and pharmacodynamic studies have demonstrated higher systemic bioavailability for esomeprazole compared with omeprazole because of less first-pass hepatic metabolism and lower plasma clearance. Researchers conducted this double-blind, multicenter study to examine the potential clinical implications of esomeprazole in the treatment of patients with gastroesophageal reflux disease (GERD). They …
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