Erratum to: “Relationship between the aggregation of nanoparticles bearing zinc ions and cytotoxicity and morphology of blood cells”

Abstract

The effect of nanoparticles bearing magnetic and nonmagnetic zinc nuclei on lymphocytes from healthy donors and leukemic cells of patients (15–20 years old) with acute B-lymphoblastic leukemia (B-ALL) and acute myeloid leukemia (AML) was considered. The studies by confocal and fluorescence microscopy showed an apoptotic effect of nanoparticles bearing zinc ions. An increase in the aggregation of the nanoparticles and cell self-aggregation, resulting in a decrease in cytotoxicity, were observed in the case of the magnetic isotope. In spite of this, cell apoptosis under the action of even aggregated nanoparticles bearing magnetic 67Zn was significantly higher than the apoptosis with lymphocytes of healthy donors and with nanoparticles bearing zinc of the total isotope composition.