Abstract
The prevalence of patients suffering from hypoxic brain damage is increasing. Long-term outcome data and prognostic factors for either poor or good outcome are lacking. This retrospective study included 93 patients with hypoxic brain damage undergoing neurological early rehabilitation [length of stay: 108.5 (81.9) days]. Clinical data, validated outcome scales (e.g. Barthel Index—BI, Early Rehabilitation Index—ERI, Glasgow Coma Scale—GCS, Coma Remission Scale—CRS), neuroimaging data, electroencephalography (EEG) and evoked potentials were analyzed. 75.3% had a poor outcome (defined as BI <50). 38 (40.9%) patients were discharged to a nursing care facility, 21 (22.6%) to subsequent rehabilitation, 17 (18.3%) returned home, 9 (9.7%) needed further acute-care hospital treatment and 8 (8.6%) died. Barthel Index on admission as well as coma length were strong predictors of outcome from hypoxic brain damage. In addition, duration of vegetative instability, prolongation of wave III in visual evoked potentials (flash VEP), theta and delta rhythm in EEG, ERI, GCS and CRS on admission were related to poor outcome. All patients with bilateral hypodensities of the basal ganglia belonged to the poor outcome group. Age had no independent influence on functional status at discharge. As with other studies on neurological rehabilitation, functional status on admission turned out to be a strong predictor of outcome from hypoxic brain damage.
Highlights
The authors would like to clarify the ethics statement in this article [1]
Before conducting this study we consulted the local ethics committee of BDH-Clinic Hessisch Oldendorf—which is not a public, official institution—and were informed that it was exempt from requiring ethics approval
After publication we became aware that the ethics committee of Hannover Medical School should have been consulted
Summary
The authors would like to clarify the ethics statement in this article [1]. Before conducting this study we consulted the local ethics committee of BDH-Clinic Hessisch Oldendorf—which is not a public, official institution—and were informed that it was exempt from requiring ethics approval. Erratum to: Outcome and prognosis of hypoxic brain damage patients undergoing neurological early rehabilitation
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