Abstract

The Research News article "Getting it together at the synapse" by Jean Marx (20 Nov., p. 1304) gave the incorrect impression that the chick agrin gene was the first to be cloned. However, Fabio Rupp, James Campanelli, and Werner Hoch (working in the laboratory of Richard Scheller at Stanford University) cloned the rat agrin gene about a year earlier and showed that the protein is made in motor neurons and is active in inducing acetylcholine receptor aggregation on muscle cells.

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