Equilibrium properties of the system (dibutyl L-tartrate)– (α-cyclodextrin)–(water) at 25°C. A 1H NMR and UV study

Abstract

The inclusion process of a '‘bifunctional’' guest molecule, butyl L-tartrate (DBT), into the α-cyclodextrin (CD) cavity has been studied with two different experimental techniques, 1H NMR and UV. The experimental data have been analyzed supposing two different reaction models: the first model supposes that only one of the two butylic residues can be included in the CD cavity, while the second one considers that also the other butylic tail can be included in a second CD cavity. This second model seems the more appropriate for describing the DBT–CD inclusion process. The results are discussed briefly.