Abstract

Correct treatment of anaphylaxis in emergency events is a key point to prevent death and subsequent events. Anaphylaxis can be quickly diagnosed if we recognize respiratory and circulatory manifestations and we correctly assess mental status. The first and most important treatment is epinephrine. After successful therapy, the clinician’s attention must be directed toward preventing recurrences- biphasic anaphylaxis and to elucidate the causes. The patient will need to be explained the importance of preventing relapse and needs to be equipped with epinephrine, which to use in critical situations. There are differences concerning therapeutic approach, recognition of symptoms and patient education, depending on physician’s experience, on patient’s education level and on socio-economic level of their country.

Highlights

  • Anaphylaxis is a major emergency, it may have an unpredictable evolution, may progress rapidly to a fatal outcome if we don’t establish the correct diagnosis, that has to be followed by rapid treatment measures.Anaphylaxis responds promptly to treatment with epinephrine, but new episodes may occur, or at least one new episode, so-called biphasic anaphylaxis, and clinicians always have to consider this situation

  • Clorpheniramine is used in a dose of 1 mg/kilo; other antihistamines: Levocetirizine, Desloratadine

  • The emergency department is very important for anaphylaxis treatment and the prevention of subsequent recurrences

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Summary

Open Access

Anaphylaxis, always a Challenge: A Therapeutic Approach on Children. Sur Genel[1,2], Sur Maria[1], Kudor-Szabadi Liana[1], Sur Lucia[1], Sur Daniel[1] and Samasca Gabriel1,2*

Introduction
Epidemiology of Anaphylaxis
Clinical Diagnosis
Flushing syndromes
Restaurant syndrome
Excess of endogenous histamine production
Another allergic manifestation
Findings
Emergency Treatment of Anaphilaxis

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