Abstract
Cerebral palsy remains as the most frequent cause of motor delay in the young children. Epilepsy can be found in about one-third of childhood patients with cerebral palsy. All seizure types can be seen. The most common types are partial complex and secondary generalized seizures. Seizures in children associated with cerebral palsy have the tendency of earlier onset, and harder control, correlated with the severity degree of cerebral palsy and the existence of mental impairment. The seizure outcome in patients with cerebral palsy is majorly poor. They usually require long-term medications and polytherapy, with more chance of intractable seizures and/or status epilepticus. The risk of seizure recurrence after stopping anticonvulsants in those with cerebral palsy remains high. Factors related to longer seizure-free period in epileptic children having cerebral palsy are normal intelligence quotient, one seizure type, mono-therapy, and spastic diplegic pattern.
Highlights
Cerebral palsy (CP) attributes to non-progressive motor impairment during brain development in the early life [1]
Factors related to longer seizure-free period in epileptic children having cerebral palsy are normal intelligence quotient, one seizure type, mono-therapy, and spastic diplegic pattern
Comparative review [5], children with CP had more incidence of epilepsy onset within one year of age (47% vs. 10%), neonatal seizures (19% vs. 3%) and status epilepticus (16% vs. 1.7%), as well as lower incidence of generalized seizure (28% vs. 59%) and seizure-free rate (37% vs. 90%), as compared to control group
Summary
Cerebral palsy (CP) attributes to non-progressive motor impairment during brain development in the early life [1]. The risk of seizure recurrence after stopping anticonvulsants in those with cerebral palsy remains high. Factors related to longer seizure-free period in epileptic children having cerebral palsy are normal intelligence quotient, one seizure type, mono-therapy, and spastic diplegic pattern.
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