Abstract

Controlled clinical trials in adults with medically refractory focal seizures treated with the RNS® system have shown that closed-loop nerve stimulation that responds to epileptic foci can reduce the frequency of disabling seizures, is well tolerated, and It is acceptable security. The reduction in seizures begins at the beginning of treatment and continues over time, reaching a median reduction of 75 to 9 years of treatment. Treatment with sensitive cortical stimulation is also related to an improvement in the quality of life and cognitive function related to the functional area being treated. In addition, the chronic dynamic cortical EEG monitoring of the RNS system provides unprecedented insights for the disease management of each patient and the research of epilepsy itself, which can improve the treatment of epilepsy in the future.

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