Abstract
The recent data on epigenetic control of differentiation in mesenchymal stem cells to be the background of embryogenesis and regeneration process in organism are considered. Epigenetic control is bases on three intramolecular mechanisms – DNA methylation, structural modification of histone proteins and microRNA active on posttranscription and posttranslation levels. As an example, the issues of stem cell differentiation in the liver are considered.
Highlights
The recent data on epigenetic control of differentiation in mesenchymal stem cells to be the background of embryogenesis and regeneration process in organism are considered
In vivo hepatic differentiation of mesenchymal stem cells from human umbilical cord blood after transplantation into mice with liver injury / J
Summary
The recent data on epigenetic control of differentiation in mesenchymal stem cells to be the background of embryogenesis and regeneration process in organism are considered. I. Epigenetic control of differentiation of mesenchуmal stem cells. Если учесть, что в зрелой ткани или органе на 1 млн специализированных клеток приходится одна МСК.
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More From: Proceedings of the National Academy of Sciences of Belarus, Biological Series
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