Epidemiology of benign tumors and pseudo tumoral lesions of the femur based on an analysis of patients receiving orthopedic care

Abstract

Benign tumors and pseudo tumoral lesions of the bones belong to the largest group ofan abnormal growth of tissue in bone, which is characterized by many specific clinical, radiological and histological features. The study of data on the spread of pathology, localization, frequency of recurrence depending on gender and age characteristics helps to determine the category of people who need a more detailed examination. Aim: Determination of the incidence of an abnormal growth of tissue in bone, the most typical localization, as well as the likelihood of recurrence and malignancy in patients with benign abnormal growth of tissue in the femoral bone. Materials and methods: Materials obtained during the analysis of casesur, as well as radiographs of 465 patients operated in the Department of Traumatology and Orthopedics of the Astrakhan State Medical University from 2 years old to 70 years, from 1977 to 2018, using nonparametric analysis methods. Differences were considered significant at r 0.05. Results: Studying various tumors depending on age, it was found that the median age of patients with aneurysmal bone cyst (13.5) was significantly lower than the median age of patients with giant cell tumor (osteoclastoma) (25), respectively. When comparing persons suffering from a metaphyseal fibrous defect (non-ossifying fibroma) and a chondroma (enchondroma), a difference was noted in the average age values, which amounted to 13.5 years and 45 years, respectively. A significant difference was also found between those with a solitary bone cyst and chondroma (enchondroma), where average was 45 years. When analyzing the significance of differences in the incidence of tumors of certain localizations depending on the patients gender, it was found that the differences are not significantly significant in any of the compared groups. A certain dependence of the tumor localization on gender is not determined, which indicates that the localization of the tumor is not related to the sex of the patient. The frequency of recurrence of an abnormal growth of tissue in femoral bone is also not related to gender. Conclusions: The primary incidence of femorals tumor is predominantly characteristic of patients aged 15 years. In the groups of patients with aneurysmal bone cyst, osteochondroma (bone and cartilage exostosis) and solitary bone cyst, the median age of a person is the smallest. In the comparison of patients with giant cell tumor (osteoclastoma), metaphyseal-fibrous defect (non-ossifying fibroma), osteoid osteoma, chondroma (enchondroma), female patients predominated, and in patients with osteochondroma (osteocartilaginous exostosis) and osteoma, male patients predominated. The incidence of recurrence in the compared groups with a diagnosis of aneurysmal bone cyst, giant cell tumor (osteoclastoma), fibrous dysplasia and chondroma (enchondroma) was significantly higher than in other groups.