Abstract
1561Background: Management of EOC is largely based on the more common serous (SC) and endometroid (EnC) subtypes, but differences in clinical characteristics of less common histologies such as clear cell (CC), mucinous (MC) and malignant mixed mullerian tumor (MMMT) are increasingly clear. Yet, treatment strategies remain uniform. Methods: We obtained data on incident EOC cases from the Surveillance, Epidemiology and End Results (SEER 13) database between 1993-2007, and compared their disease characteristics. Survival analysis was performed using Kaplan-Meier and flexible parametric models. Results: Of 25358 incident EOC cases, 15405 (60.8%) had SC, 2748 (10.8%) EnC, 4264 (16.8%) MC, 1913 (7.5%) CC and 1028 (4.1%) MMMT. Age adjusted incidence rate per 100K (standard US 2000 population) was highest in SC (5.3), followed by EnC (1.5), MC (1.0), CC (0.7) and MMMT (0.4). The proportion of CC, MC and MMMT was more common in Asians (15.1%), American Indians (15.4%) and Blacks (5.4%) respectively (p<0.001). Mean...
Published Version
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