Abstract

Epidemiology and diagnosis of the severe acute viral respiratory infections in patients admitted at IBN Sina University Hospital Rabat- Morocco

Highlights

  • Several viruses are accused in the severe acute respiratory infections and their diagnosis profits from the assets of the multiplex PCR.The aim of this study was to describe the general epidemiology of these infections in hospitalized children and adults and to compare the diagnostic performances of the multiplex to an uniplex PCR

  • We diagnosed a viral infection in 65% patients and the frequency was significantly higher in the pediatric population (73 vs 46%, p= 0,002)

  • Respiratory syncytial virus (RSV), and human metapneumovirus showed a seasonal peak during the winter season, while enterovirus, adenovirus, parainfluenza virus 3 and rhinovirus do not have marked seasonal variation

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Summary

Introduction

Several viruses are accused in the severe acute respiratory infections and their diagnosis profits from the assets of the multiplex PCR (polymerase chain reaction).The aim of this study was to describe the general epidemiology of these infections in hospitalized children and adults and to compare the diagnostic performances of the multiplex to an uniplex PCR. The acute respiratory infections remain the major cause of morbidity and mortality worldwide among children, the elderly, the immunocompromised persons and those suffering of a subjacent lung or cardiac disease [1]. They represent as a consequence, a public health problem. The clinical secondary symptoms with these various viruses can overlap and increase the risks of errors during the clinical diagnosis [9] This requires a precise and fast laboratory diagnosis in order to improve the therapeutic decisions and the outcome of the patients

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