Abstract

Severe depression beside the pathological mood, also denotes the cognitive, perceptual, and motor activities that are psychopathologically related to the scope of all psychic dynamics, which means cognitive, conative, and emotional. This mental illness covers a large area of ​​the affective life of a man with a wide range of severe depression classified by ICD - 10 - F 32, F32.2 and F 32.3. By using a retrospective approach in the research will be gathered data from medical histories on biological and social factors that act positively or negatively on the occurrence and course of major depression. The research aims to determine the total number of patients with severe depression treated in hospital conditions in the Psychiatric Hospital ,,Skopje’’ - Skopje for a period of 5 years from 2013-2017 in order to get a clear picture of the factors and specific predictors that lead to development of major depression. Within the research methods all the parameters contained will be calculated so that it can be concluded that the predictors influence and differ from other stakeholders responsible for etiopathogenesis, although they have a mutual influence. From the obtained data we expect to obtain the scope of the influence of socio-demographic data on the occurrence of Major Depression and sequelae of the disease. Keywords: severe depression, cognitive function, affectivity, mental illness, medical history DOI: 10.7176/JHMN/95-06 Publication date: November 30 th 2021

Highlights

  • Depressive illnesses affect a wide range of mental health changes, from sadness and fear, insomnia with psychosomatic disorders, to psychotic mental disorders such as severe depression, a chronic diagnostic entity (1,2)

  • The World Health Organization estimates that in all parts of the world, the majority of the population suffers from mental illness that manifests itself in depressive phenomena at least once in a lifetime regardless of gender, age, demographic and sociocultural characteristics, religious beliefs and demographic and sociocultural characteristics (3)

  • And nosologically, depression is an affective disorder with a primary impairment of cognitive functions, alteration of affectivity, psychomotor retardation, and social isolation

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Summary

Introduction

Depressive illnesses affect a wide range of mental health changes, from sadness and fear, insomnia with psychosomatic disorders, to psychotic mental disorders such as severe depression, a chronic diagnostic entity (1,2). The World Health Organization estimates that in all parts of the world, the majority of the population suffers from mental illness that manifests itself in depressive phenomena at least once in a lifetime regardless of gender, age, demographic and sociocultural characteristics, religious beliefs and demographic and sociocultural characteristics (3). Research on hospitalized patients diagnosed with severe depression suggests that depressive disorders are among the top two leading causes of disability due to illness. The consequences of this disease and the loss of health are great. It is estimated that over 300 million people suffer from depression, which is equivalent to 4.4 percent of the world's population. The WHO does not have any data on the prevalence of severe depression in the Republic of North Macedonia for the period from 2005 to 2016 (which is the motive for starting this research) while in neighboring countries the data are: Albania 4.8%, Bulgaria 5.2%, Greece 5.7% (5)

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