Abstract
Objectives: To explore factors affecting male infertility to provide evidence for the etiology, prevention intervention and reproductive health services for male infertility. Methods: A total of 16,286 male patients from 2011 to 2016 in Reproductive Hospital Affiliated to Shandong University, China were selected. We conducted surveys on these cases and analyzed the influencing factors of male infertility using logistic regression models. Results: Univariate logistic regression analysis results showed that there was a statistically significant difference in educational levelcareer distribution and smoking between the case group and the control group (p<0.05)After controlling confounding factors in the multivariate logistic regression model, suffering from mumps or varicocele or orchitis (OR=1.228, p<0.001) in the past and smoking (OR=1.159, p=0.010) was associated with male infertility. Conclusion: Suffering from mumps or varicocele or orchitis in the past and smoking could increase the risk of male infertility. Measures should be taken to reduce the incidence of male infertility
Highlights
Infertility is a term doctors use if a woman can not be pregnant due to her spouse after at least one year of trying when they did not take any contraceptive measures
There was no statistical significance between the case group and the control group, the incidence rate of male infertility in the case group living in cities was significantly higher than that in the rural areas
We found that 5,965 subjects had varicose veins, which is consistent with the result of Foresta [16]
Summary
Infertility is a term doctors use if a woman can not be pregnant due to her spouse after at least one year of trying when they did not take any contraceptive measures. Most studies demonstrated that the decline of semen quality was associated with the deterioration of the global environment, the growing incidence of male reproductive diseases, the change of lifestyle and bad living habits. Male infertility has lead to heavy mental pressure, and become one of the main reasons for social and family instability. Semen routine analysis is an important test for the clinical evaluation of male fertility [1,2,3].
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