Epidemiologic study of 230 cases of testicular/paratesticular tumors or masses: 15-year experience of a single center

Abstract

PurposeThis study retrospectively investigated the cases of testicular tumors/masses treated in our center from 2002 to 2017 and analyzed their epidemiologic features. MethodsData were collected by searching our center's database using “testicular tumor” or “testicular mass” as keywords. Patients not operated in our hospital were excluded. Preoperative serum alpha-fetoprotein (AFP) levels were reviewed in germ cell tumor (GCT) cases and analyzed to predict malignancy in various age groups. ResultsIn total, 230 cases were identified: 151 were benign (78 in the left, 72 in the right, and 1 bilateral) with 3.63years mean age during the operation, and 79 were malignant (42 in the left, 36 in the right, and 1 bilateral) with 2.21years mean age during the operation. Main pathological diagnoses were mature teratoma (92, 40.00%), yolk sac tumor (53, 23.04%), dermoid cyst (23, 10.00%), embryonic carcinoma (15, 6.53%), immature teratoma (14, 6.09%), benign cyst (8, 3.48%), Leydig cell tumor (6, 2.61%), and paratesticular rhabdomyosarcoma (5, 2.17%). All GCT cases with AFP >1000ng/ml, >100ng/ml, >20ng/ml were malignant in <7-, 7–9-, and ≥10-month-old groups, respectively. ConclusionsRadical inguinal orchiectomy without biopsy is suggested in 7–9- and ≥10-month-old cases with AFP >100ng/ml and >20ng/ml, respectively. Type of studyRetrospective Study. Level of evidenceLevel III-IV.