Abstract
Background of study aims and objective:Epicardial fat thickness is a novel parameter for predicting outcome and assessment of severity of coronary artery disease. Our present study aims to establish an association between epicardial fat thickness and coronary artery disease. Materials & Methods: Patients of suspected CAD underwent coronary angiography. 100 subjects proven as confirmed cases were included in the study. Routine clinical examination, risk factor profile and anthropometric variables were also done. Severity of CAD was assessed using Gensini Score. Epicardial fat thickness was measured using 2D ECHO. For comparative analysis, 50 healthy individuals were also included in the study. Results: Epicardial fat thickness was significantly higher in cases (7.53 ± 1.79 mm) than controls (4.24 ± 1.09 mm). Female sex, hypertension, dyslipidemia, obesity were observed to affect EFT significantly. No difference in mean EFT was observed with age, diabetes, smoking, ECG changes and arterial territory involvement. BMI and Gensini scores both showed strong positive correlation with epicardial fat thickness. Conclusion: Epicardial fat thickness is associated and linearly correlates with onset and severity of CAD.
Highlights
Coronary Artery Disease (CAD) is a complex chronic inflammatory disease characterized by remodeling and narrowing of coronary arteries supplying the heart most commonly due to atherosclerotic changes [1]
Background of study aims and objective: Epicardial fat thickness is a novel parameter for predicting outcome and assessment of severity of coronary artery disease
Our present study aims to establish an association between epicardial fat thickness and coronary artery disease
Summary
Coronary Artery Disease (CAD) is a complex chronic inflammatory disease characterized by remodeling and narrowing of coronary arteries supplying the heart most commonly due to atherosclerotic changes [1]. Epicardial fat thickness (EFT) is a promising novel marker for assessing risk and progression of CAD. It is the true visceral depot of heart with close proximity to the myocardium and shares the same microcirculation [3]. It has shown to have association with established risk factors of CAD such as diabetes, dyslipidemia, hypertension and smoking [10] [11] [12] [13] [14]. Epicardial fat thickness is a novel parameter for predicting outcome and assessment of severity of coronary artery disease. Our present study aims to establish an association between epicardial fat thickness and coronary artery disease. Conclusion: Epicardial fat thickness is associated and linearly correlates with onset and severity of CAD
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call