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Abstract
A diagnostic work-up leading to a cancer diagnosis is a severely stressful experience as illustrated in the dramatic rise in distress, suicide, and cardiovascular deaths after diagnosis. Data are scarce on the underlying interaction between the psychological and biological components of stress during this critical time window. The aim of this study was to assess pre- to post diagnosis change in symptoms of psychological distress and urinary excretion of catecholamines in this population.
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