Abstract
To assess the feasibility of assessing the cerebroplacental resistance (CPR) at the time nuchal translucency (NT) assessment and to establish a normogram for the CPR in an unselected Lebanese population. Prospective study on 200 gravidas with spontaneous conception of singleton gestations presenting for NT assessment between 12w0d and 13w6d at 2 centres in Lebanon. Maternal BMI, fetal CRL, BPD and NT were obtained. In addition, colour Doppler, using high definition flow and first trimester cardiac presets, was utilised to measure the pulsatility index of the middle cerebral artery (MCA) and the umbilical artery (UA) in order to calculate the CPR when possible. The normogram for the CPR in our population was established. All exams were carried out transabdominally by 2 experienced sonologists. The PI of the MCA and UA was successfully measured and CPR calculated in 142/200 (71%) of cases. There was no effect of maternal BMI, fetal CRL or BPD on successful visualisation. The normogram for the CPR in our population was established. The results show no significant relation between CPR and CRL or CPR with BPD, with best fitted linear regression modelling yield: CPR =0.70 +0.004 CRL (R2 =0.003) and CPR =0.31 +0.029 BPD (R2 =0.0194) respectively. It is feasible to measure CPR in 71% of fetuses at the time of NT assessment. This may prove helpful in early assessment of fetuses with growth restriction or congenital heart defects.
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