Abstract
We encounter a large number of cases of lumbar disorder presenting with sciatica in routine clinical practice. However, systemic vasculitis could also possibly present with sciatic nerve neuropathy or similar symptoms. Delayed diagnosis may hinder successful intervention for this condition. Eosinophilic granulomatosis polyangiitis (EGPA), also known as Churg–Strauss syndrome (CSS) or allergic granulomatosis angiitis (AGA), is a relatively rare condition characterized by bronchial asthma, eosinophilia, and systemic necrotizing granulomatosis angiitis affecting small and medium-sized vessels [1]. The symptoms of this progressive condition are reported to be well managed by corticosteroids or other immunosuppressants [1]. Examination of some molecular targeting drugs led to expectations of favorable clinical treatment [2, 3]. However, this condition may have a high rate of relapse [4], and may cause severe secondary disorders such as intestinal perforation, intestinal hemorrhage, myocardial infarction, or central nervous system disorders, which may aggravate functional or vital prognosis [4–6]. We report a case of AGA which mimicked lumbar disease, expressing symptoms such as unilateral acute sciatic nerve neuropathy and foot-drop. Case report
Published Version
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