Abstract
To the Editor: —The reader of the article Eosinophilic Granuloma of Bone: Report of Case with Multiple Lesions of Bone and Pulmonary Infiltration, by A. Weinstein, H. C. Francis and B. F. Sprofkin, published in this journal ( 79 :176 [Feb.] 1947) may become confused on the issue of whether eosinophilic granuloma of the bone is newly discovered entity or whether it is part of systemic disorder formerly described under different designations such as Schuller-Christian disease (Rowland, 1928), lipid granulomatosis (by Chester, 1930, and Fraser, 1934) and essential xanthomatosis of the normocholesteremic type (Thannhauser and Magendantz, 1937). The following presentation illustrating historically the conception of the pathogenesis of the may contribute toward the clarification of some misunderstanding concerning its classification. Schuller described in 1915 1 of the membraneous bones of the skull, referring later, in 1921, 2 to a peculiar syndrome of dyspituitarism. Christian in 1919 3 called attention to clinical syndrome consisting in defects in membraneous bones,
Published Version
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