Abstract
Eosinophilia is a relatively common finding in patients with AIDS and may be due to HIV infection alone or due to several eosinophil-associated disorders unrelated to HIV. There is evidence to support a special role for the eosinophil in the immunologic changes associated with AIDS. This article reviews the biology of the eosinophil in relation to the immunologic changes that occur with HIV infection. We outline the key features in the clinical assessment of eosinophilia in the AIDS patient, provide a differential diagnosis by organ system, and discuss therapeutic considerations.
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