Abstract
Levels of serum glutamic pyruvic transaminase (SGPT), serum glutamic oxalacetic transaminase (SGOT), and serum alkaline phosphatase (SAP) were measured in duck blood. Enzyme activity of groups receiving up to 64 iron shot orally did not differ significantly (p <0.05) from that of controls. Significant increases in SGPT and decreases in SAP accompanied oral lead poisoning. Levels of GOT and GPT, but not AP, were much higher in control red cells than in plasma or serum. Among the tissues studied, heart contained the greatest relative amount of GOT and among the least relative amounts of GPT and AP. Kidney contained the highest relative concentrations of GPT, while duodenum and kidney had the highest AP levels. The increase in SGPT of lead-poisoned ducks may reflect hepatic, renal, or skeletal muscle damage, although this damage was not associated with a significant increase in SGOT. The decreased SAP activity probably reflected a direct inhibition of the enzyme by lead. 22 references, 3 figures, 1 table.
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