Abstract

Platelet hexokinase, phosphofructokinase, phosphoglycerate kinase, enolase, pyruvate kinase, lactic dehydnogenase, glucose-6-phosphate, dehydrogenase, and glutamic-oxaloacetic transaminase activity was assayed in platelets from newborn infants and contrasted with those of adults. Platelet phosphofnuctokinase activity was decreased and platelet phosphoglycerate kinase and glutamic-oxaloacetic transaminase activity were elevated in the platelets of newborn infants. It would appear that certain biochemical properties of the erythrocytes of the newborn are shared by the platelets as well. The metabolic consequences of these differences remain to be explored.

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