Abstract
A lipase-catalyzed, mild and environmentally friendly synthesis of polyhydroxyalkyl pyrroles from various unprotected sugars, benzoylacetonitriles and NH4OAc/benzylamine in water was reported for the first time in this work. Moreover, the synthetic potentiality of this enzymatic method was demonstrated by easy isolation of the final products using filtration. This green synthesis and purification approach not only enriches the strategies for synthesis of polyhydroxyalkyl pyrroles, but also expands the application of lipase in organic synthesis.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call