Abstract A multi-floor manufacturing in residential districts of huge city promotes decongestion of urban traffic and satisfy the population’s demand for essential goods. City manufacturing and its supply chain entail several challenges related to the sustainable development of a large agglomeration. Environmental problems impose significant constraints on such manufacturing activities and production waste in the urban environment poses a real problem that needs to be addressed by special research. This paper discusses integrated sustainable production waste management for a city multi-floor manufacturing cluster, consisting of a group of production buildings and a supporting logistics node. In line with the theory of integrated sustainable waste management, three key components are addressed: waste management stakeholders, components of the waste management system, and the technical, environmental and legal aspects of a city multi-floor manufacturing cluster. The goal of the paper is to develop a concept for a model of environmental sustainable waste management in a city multi-floor manufacturing cluster, aimed at ensuring the system safety: human - technical facility - environment. This model can serve as a basis for the development of appropriate logistics chains for production waste management considering their hazardousness indicator. The versatility of the model will allow it to be widely used, and when its stages and working principles are embedded in the practice of city multi-floor manufacturing, proper control over the waste management process can be achieved. The application of the proposed model of integrated sustainable production waste management in the practice of the city multi-floor manufacturing clusters will contribute to the environmental sustainability of its operation.

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