Environmental and biomedical applications of AgNPs synthesized using the aqueous extract of Solanum surattense leaf

Abstract

A novel eco-friendly and biocompatible method has been used with the help of Solanum surattense aqueous leaves extract to synthesis silver nanoparticles (AgNPs). The cost-effective green synthesis route has been given much care to ensure an environmentally friendly and straightforward approach, as it is most demanded in the biomedical industry. The proposed novel synthesis method offers additional compensations over other synthesizing approaches. Different analytical systems such as UV–vis, IR, XRD, DLS, SEM, EDAX, XPS, and TEM characterization techniques were used to understand the quality of the green synthesized nanoparticles for biomedical applications. The surface plasmon resonance peak of green synthesized silver nanoparticles at 446 nm was observed by UV absorbance spectral analysis. The XRD, SEM, and TEM analysis using to study the crystal structure, particle size, and surface morphology of the AgNPs. The results confirmed the synthesized spherical shape silver nanoparticles were crystallized in a face-centered cubic structure. The zeta potential measurement was used to authorize the excellent stability of AgNPs employing the dynamic light scattering method. FTIR spectral study confirmed that phytocompound participate in the bioreduction as well as stabilization of biosynthesized AgNPs by Solanum surattense. Also, the phytochemical content acts as the capping agent on surface AgNPs. The synthesized silver nanoparticles are subjected to antibacterial activity against both gram-positive and negative pathogenic bacteria for finding suitability in biocompatible applications. Also, the cytotoxicity of AgNPs was studied against the human breast cancer cell line and compared with one of the commercially available cancer drugs. Also, we have shown that the prepared AgNPs could serve as an excellent photocatalyst for degrading the Rhodamine B (RhB) dye and Acid Violet 7 (AV 7) dye under direct sunlight radiation.