Enteral and parenteral nutrition in the treatment of elderly patients with acute pancreatitis complicated with hyperlipidemia

Abstract

Objective To study the effect of enteral nutrition combined with parenteral nutrition in the treatment of elderly patients with acute pancreatitis complicated with hyperlipidemia. Methods 50 patients with acute pancreatitis and hyperlipidemia were enrolled, and they were randomly divided into observation group (n=25) and control group (n=25) according to the digital table.The patients in the observation group were given enteral nutrition combined with parenteral nutrition, the control group was treated with parenteral nutrition support, The effect of nutrition support was compared between the two groups. Results The blood and urine amylase levels in the two groups after 8d were (69±11)U/L and (184±24)U/L, (72±21)U/L and (177±21)U/L, respectively, while the levels were (278±32)U/L and (884±108)U/L, (271±31)U/L and (863±119)U/L after 4d, which after 1d were (574±57)U/L and (2 278±321)U/L, (593±61)U/L and (2 311±343)U/L, respectively, and the levels after 8d were significantly lower than those after 4d (the observation group: t=30.883, P=0.000; t=31.636, P=0.000.The control group: t=26.574, P=0.000, t=28.385, P=0.000), and the levels after 4d were significantly lower than those after 1d (the observation group: t=22.641, P=0.000; t=20.580, P=0.000.The control group: t=23.529, P=0.000, t=19.942, P=0.000). The albumin and prealbumin of the control group after 8d were (31.49±3.17)g/L and (90.51±20.07)mg/L, respectively, which of the observation group were (33.49±3.08)g/L and (103.73±22.89)mg/L, respectively, there were statistically significant differences between the two groups (t=2.262, P=0.028; t=2.171, P=0.035). The total cholesterol and triglyceride levels in the observation group were (2.81±0.81)mmol/L and (2.74±0.24)mmol/L, respectively, which in the control group were (2.93±0.73)mmol/L and (2.67±0.31)mmol/L, respectively, which were significantly higher than those after 1d (the observation group: t=7.798, P=0.000, t=3.371, P=0.003; the control group: t=8.079, P=0.000, t=2.560, P=0.000). Conclusion For the acute pancreatitis elderly patients with hyperlipidemia, the enteral nutrition combined with parenteral nutrition support can effectively improve the patients' clinical symptoms and signs, promote the remission. Key words: Enteral nutrition; Parenteral nutrition; Pancreatitis; Hyperlipidemia