Abstract
Relying on the synergistic action on contractility of enoximone and dobutamine when concomitantly infused, 25 patients with their first acute Q-wave anterior myocardial infarctions underwent conventional low-dose dobutamine echocardiography (LDE) and enoximone very–LDE to assess myocardial viability in severely dysfunctioning areas. Images were recorded at peak of pharmacodynamic effect of drugs and 4 months after revascularization. At peak-dose stage of LDE and enoximone very–LDE the regional infarct zone wall-motion score significantly decreased from the basal value of 25.6 ± 2.9 to 16 ± 6.0 ( P < .001) and to 14.5 ± 5.2 ( P < .001), respectively. A high correlation was found by comparing the wall-motion score of each patient calculated at peak effect of combined drug administration with follow-up values ( r s = 0.9). Enoximone very–LDE has proven to be a new test useful to evaluate viability in asynergic segments especially when the results of conventional tests are questionable.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call