Abstract

As an imaging manifestation of cerebral small vascular disease, the relationship between enlarged perivascular spaces (EPVS) and cognitive impairment has attracted much attention. Clinical studies have shown that EPVS may be present in the general population and in patients with cognitive impairment caused by neurodegenerative or cerebrovascular diseases. Further studies have showed that EPVS may be an independent risk factor for cognitive impairment. This article reviews the pathogenesis of cognitive impairment in individuals with EPVS. Key words: Cerebral Small Vessel Diseases; Cognition Disorders; Magnetic Resonance Imaging; Alzheimer Disease; Perivascular Spaces

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