Abstract
AbstractWe describe a simple and inexpensive method to enhance the sensitivity or improve the detection limit of solution-phase localized surface plasmon (LSPR) sensors of metallic nanoparticles. The substrate surface contains metallic nanostructures which are replicated from DVD disks via the standard soft lithography. By mixing BSA molecules with nanoparticle solution, we demonstrate that the wavelength shift due to the absorption of BSA molecules on nanoparticle surfaces is amplified by more than an order of magnitude in comparison to that over a smooth flat surface.
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