Abstract
We study lepton flavor violating (LFV) $B$ decays in a general two Higgs doublet model with sub-TeV exotic scalars. Two different parameter spaces are explored: one dominated by extra top Yukawa coupling $\rho_{tt}$, the other by LFV couplings relevant for the muon $g-2$ anomaly. In the first case, flavor constraints such as $\ell \to \ell^\prime\gamma$, $h \to \ell\ell^\prime$ imply LFV $B$ decays are far below experimental sensitivities. The second case needs to be close to the alignment limit, but $B_q \to \tau\mu$ and $B \to (K, \pi) \tau\mu$ rates can lie within the sensitivities of Belle II and LHCb Upgrade II. Neutral $B$ meson mixings and $B,\, K,\, \pi \to \ell \nu$ decays provide important flavor constraints on parameter space. $B$ decays involving $e$-$\tau$ violation are constrained by $\mu\to e$ processes.
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