Abstract

Hypophosphatemia has serious metabolic effects that may increase morbidity and mortality in many illnesses. The present study was designed to know the incidence and severity of hypophosphatemia in a cohort of patients with acute and chronic liver diseases.The acute liver disease group comprised of cases in which the liver damage has been induced by type-A and type-B viral hepatitis. The chronic liver disease group comprised of cases in which the liver damage in the form of hepatitis and cirrhosis has been induced by alcohol. All the patients with acute and chronic liver diseases showed significantly lower phosphate levels when compared to the control group. However, significant difference in phosphate levels between the acute and chronic liver disease groups were not observed. Whether frequent monitoring of serum phosphate levels and early treatment of severe hypophosphatemia will alter the prognosis of patients with acute and chronic liver diseases should be determined in further studies.

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