Abstract

The present study was undertaken to evaluate activity of juice of bulbs of Allium cepa on isolated frog's heart. Different parts of this species are used in India for a wide range of medicinal purposes. Effect of juice of bulbs of Allium cepa was studied by using isolated frog heart perfusion technique (IFHP). Cardiotonic activity was studied on both normal and hypodynamic hearts. The present preliminary studies confirm the better cardiotonic activity of juice of bulbs of Allium cepa as compared to digoxin. Further studies can confirm the reduced toxicity and this will be the advantage of juice of bulbs of Allium cepa over digitalis. Thus, in future it will be interesting to isolate the active chemical constituents which are responsible for the cardiotonic activity.

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