Abstract
Vitamin D is a fat-soluble steroid hormone that is crucial for human health. Since long the role of epidermal keratinocytes in the UVB-induced photochemical conversion of 7- dehydrocholesterol to vitamin D3 is known, and also for the enzymatically controlled hydroxylation of the photolysis product. This whole process results in the formation of the biologically active final product 1, 25-(OH)2 D3 (Calcitriol). Moreover recently various research articles have shown benefits of calcitriol and various other vitamin D analogues having a therapeutic role in various dermatologic conditions like psoriasis, atopic dermatitis, acne, vitiligo owing to its anti-inflammatory, anti- proliferative action. The present review shows a summary of role of vitamin D in dermatologic perspective.
Published Version
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