Abstract
The bioactive compounds were screened by gas chromatography-mass spectrometry (GC-MS) method. Twenty one bioactive phytochemical compounds were identified in the methanolic extract of Mentha viridis using GC-MS method. The identification of phytochemical compounds is based on the peak area, retention time, molecular weight and molecular formula. GC-MS analysis of M. viridis revealed the existence of the 3,6-Octadecadiynoic acid, methyl ester, 2,5-Dimethyl-4-hydroxy-3(2H)-furanone, 4H-pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl, benzofuran, R-Limonene, 2-methoxy-4-vinylphenol, 2-hydroxy-5-methylbenaldehyde, tetra-acetyl-d-xylonic nitrile, Ficusin, Phen-1,4-diol, 2,3-dimethyl-5-trifluoromethyl, n-Hexadecanoic acid, 7-Methyl-Z-tetradecen-1-ol acetate, Ethyl 9,12,15-octadecatrienoate, Methyl 19-methyl-eicosanoate, Ethyl iso-allocholate, and Tocopherol. Five new bioactive chemical compounds 3-(N,N-Dimethyllayrylammonio), 1b,4a-eboxy-2H-cyclopenta [3,4]cyclopropal[8,9] cycloundec, 5H-Cyclopropa[3,4]benz [1,2-e]azulene-5-one, 2,2,4-Trimethyl-3-(3,8), 12,16-tetramethyl-hepta deca, and 4H-Cyclopropa[5,6]benz [1,2:7,8] azulene[5,6-b] oxiren-4-one are described and may in future be suitable sources for phytotherapy purposes. Mentha viridis contain chemical constitutions which may be useful for various herbal formulation exhibiting cardiac tonic, analgesic, antiasthamatic, anti-inflammatory and antipyretic properties. Key words: Bioactive compounds, chromatography-mass spectrometry (GC-MS) analysis, Mentha viridis.
Highlights
Lamiaceae family consists of 200 genera and more than 4000 species (Ramesh et al, 2007)
The phytochemical investigations on the Mentha species revealed that they possessed flavonoids and their glycosides, phenolic compounds, triterpenoids, steroids, and lignans (Monte et al, 1998; Areias et al, 2001; Ali et al, 2002; Zheng et al, 2007)
The objective of this research was to determine the phytochemical composition of methanolic extract of Mentha viridis
Summary
The phytochemical investigations on the Mentha species revealed that they possessed flavonoids and their glycosides, phenolic compounds, triterpenoids, steroids, and lignans (Monte et al, 1998; Areias et al, 2001; Ali et al, 2002; Zheng et al, 2007). Many species within this family are medicinal plants that apply in food, row and cooked forms and in human disease therapy (Santos et al, 2012). Their leaves have been consumed as herbal tea and spice (Iscan et al, 2002)
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