English

Abstract

BACKGROUND: Medical expulsive therapy has been proven to enhance stone expulsion rate, decrease stone expulsion time and decrease the use of analgesics in lower ureteric calculus. But adequate data is not available on the efficacy of medical expulsive therapy for mid ureteric calculus. Tamsulosin is the most common agent used in medical expulsive therapy along with analgesics. Hence we have studied the efficacy of medical expulsive therapy in this study. PURPOSE: To determine the efficacy of medical expulsive therapy in mid ureteric calculi of up to 10 mm in size- Comparing the results with Placebo and lower ureteric calculi. MATERIAL AND METHODS: It was a prospective randomized study conducted between September 2011 to march 2013. 60 patients with mid ureteric calculi of ≤10 mm and 60 patients with lower ureteric calculi of ≤10 mm were randomly selected for the study. Patients in the study group received 0.4 mg of Tamsulosin and Aceclofenac 100 mg SOS, whereas the control group received only analgesics. Statistical methods used: All the data was collected and analyzed using SPSS 16.0 (2007) software. RESULTS: The stone expulsion rate was higher for patients with mid ureteric calculi who received medical expulsive therapy compared to controls (56.6% Vs. 20%). The stone expulsion rate was higher for patients with lower ureteric calculi compared to patients with mid ureteric calculi (93.3% Vs. 56.6%). CONCLUSION: Medical expulsive therapy can be used with success in patients with mid ureteric calculi up to 10 mm in size. Medical expulsive therapy is more beneficial in patients with lower ureteric calculi as compared to patients with mid ureteric calculi.