English

Padhi Sb,Pradhan S,Dash N,Behera G,Behera S,Mishra A,Beza S,Panigrahi M,Swain P,Baidya S,Behura S,Ratha N,Panigrahi H

doi:10.9735/0975-3087.2.2.88-95

Abstract

Computational biology is a term coined from analogy to the role of physical sciences, is now coming into its own as a major element of contemporary biological and biomedical research. In the sharp in this pattern, over past few years, experiments in life sciences in the academic institutions have begun to recognize the value of bioinformatics and computational biology in the field of algology. Cyanobacteria (also known as blue-green algae) are a group of extraordinarily diverse Gram-negative prokaryotes that originated 3.5 billion years ago. After the advent of bioinformatics in the field of algology, complete genome sequences of Cyanobacteria have been reported in more than 30 species and strains including unicellular. The filamentous cyanobacterium Anabaena sp. PCC 7120 (further referred to as Anabaena sp.) is a model system to study nitrogen fixation, cell differentiation, cell pattern formation and evolution of plastids. It is a multicellular photosynthetic microorganism consisting of two cell types, vegetative cells and nitrogen fixing heterocysts. The nucleotide sequence of the entire genome of a filamentous Cyanobacterium, Anabaena sp. Strain PCC 7120, was determined. This study focuses on the function and dynamics of the proteome of the Gram-negative outer membrane in Anabaena sp.

Highlights

In looking at the origin and growth of computational biology, we see a parallel to molecular biology, which had its origins 40-50 years ago as the tools of multiple disciplinesespecially physics, chemistry biophysics, microbiology and genetics were applied in new ways, a vigorous and often rigorous reductionism attack on central barriers to understanding the mechanisms by which simple bacteria and viruses function
Like proteins [11], establish physical contact with the inner membrane components, which provide them with energy from the cytoplasmic sources to drive the active transport across the outer membrane
The phylogenetic tree (Fig 2) that was obtained from Phylip was an unrooted tree with different branch lengths

Summary

Introduction

In looking at the origin and growth of computational biology, we see a parallel to molecular biology, which had its origins 40-50 years ago as the tools of multiple disciplinesespecially physics, chemistry biophysics, microbiology and genetics were applied in new ways, a vigorous and often rigorous reductionism attack on central barriers to understanding the mechanisms by which simple bacteria and viruses function. The outer membrane is a border of a Gram-negative cell, such as Anabaena sp. For this reason the structure and the function of the outer membrane are essential for establishing the contact and compound exchange with the surroundings, sensing the outside conditions and reacting to them [5]. Since the outer membrane proteins are crucial in all these processes, revealing the protein composition of the Anabaena sp.

Results

Conclusion