Abstract

IT is now recognized, especially from studies on the physiology of adult epidermis, that the energy requirements of mitotic activity are high1. There is a marked diurnal rhythm in epidermal mitotic activity, and this appears to be determined by variations in the rate of uptake of glucose from the blood. Hair bulbs contain cells which are epidermal derivatives; but their mitotic activity follows a remarkably individual pattern, which is not influenced by the diurnal rhythm. Waves of hair-growth pass slowly across the body of a mouse, and, according to the position of these waves, the hair bulbs are either completely quiescent or are engaged in the most violent mitotic activity.

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