Abstract

When septic patients progress to endotoxin shock, they present a high mortality rate. The mortality rate of septic patients with multiple organ failure has been reported to be 30–80%. The endotoxin adsorption method (PMX-DHP: Toray Industries, Inc., Tokyo, Japan) has been used for treatment of patients with severe sepsis and septic shock primarily caused by Gram-negative infections in Japan. We also reported that PMX-DHP removed plasma endotoxin and improved hemodynamic parameters in clinical trials [1]. The purpose of this study was to assess the changes of procalcitonin (PCT) values during PMX-DHP.

Highlights

  • The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality

  • The goal from this study is to evaluate weaning predictor indexes in patients during weaning from mechanical ventilation (MV)

  • This study aims to evaluate the effects of the threshold in such situations

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Summary

Introduction

The aim of this study was to elucidate the impact of ICU-acquired infection on ICU and hospital mortality. Methods A total of 48 community patients (36 men, 11 women, age 50.17 ± 17.974 years, APACHE II score 13.51 ± 6.153) who were expected to stay in the ICU for >5 days were included in this study. Specific examples of feedback are as follows: ‘good update of management plan reinforces need for taking into account concurrent medication when resuscitating patients’, ‘nice simple messages with good starting points for trying to deal with these complicated patients’, ‘useful data on risk of recurrence as this is a question often asked by patients’ This feedback was encouraging as it showed how the primary care professionals planned to change their practice to improve patient outcomes as a result of the learning. The course was considered excellent by 63% of the participants and good by 36%

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